Formulation and evaluation of transdermal drug-delivery system of isosorbide dinitrate
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چکیده
منابع مشابه
Buccoadhesive Drug Delivery System of Isosorbide Dinitrate: Formulation and Evaluation
Buccoadhesive buccal delivery systems for isosorbide dinitrate in the form of unidirectional buccal films were developed and characterized for improving bioavailability. The films were formulated by solvent casting method using different bioadhesive polymers like Carbopol 934P and polyvinyl pyrrolidone by using two different plasticizers propylene glycol and diethyl phthalate. Unidirectional re...
متن کاملFormulation and evaluation of transdermal drug-delivery system of isosorbide dinitrate
The purpose of this study was to develop a reservoir-type transdermal delivery system for isosorbide dinitrate (ISDN). The developed patch consisted of five layers from bottom to top, namely, a temporary liner, an adhesive layer, a rate-controlling membrane, a reservoir and a backing. The effects of chemical penetration enhancers, reservoir materials and rate-controlling membranes on the releas...
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The aim of this study was to prepare a pentazocine (PTZ) matrix-type transdermal drug delivery system (TDDS) using acrylic pressure-sensitive adhesives. Among the five Duro-Tak adhesive polymers tested (87-9301, 87-2677, 87-201A, 87-2196, 87-2852), in vitro dissolution studies demonstrated the highest PTZ release flux from the Duro-Tak 87-9301 matrix. In addition, the effects of permeation enha...
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Background and purpose: Tadalafil has gained wide clinical acceptance in treatment of erectile dysfunction due to its long treatment window and lower potential for visual impairment. Transdermal drug delivery prevents systemic elimination, drug-drug and food-drug interactions, and reduces side effects by reducing the dose of the drug. The aim of this study was to evaluate the effect of microemu...
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ژورنال
عنوان ژورنال: Brazilian Journal of Pharmaceutical Sciences
سال: 2015
ISSN: 1984-8250
DOI: 10.1590/s1984-82502015000200015